Eye (Ocular) Changes

Ocular Changes (ManageCRC.com)
Changes in visual fields and acuity have been attributed to a number of pharmaceutical agents, including narcotics, as well as to chemotherapeutic agents such as the antimetabolites, alkylating agents, taxanes, and platinum agents. This article, aimed at oncology nurses, advises that reported adverse effects vary from seemingly mild changes such as dry eyes and blurred vision, which are generally transient, to more severe and sometimes permanent changes, such as retinal damage, glaucoma, and cataracts. Medications taken for comorbid conditions also can cause ocular changes; therefore, a full medication assessment should be undertaken when a patient reports visual changes. In certain types of cancer known to metastasize to the brain, persistent visual changes should prompt radiologic examination of the brain to rule out brain metastases. Links to assessment tools and patient care management protocols are provided. [9/06]