Targretin (bexarotene) : Ligand Pharmaceuticals : Retinoid
Role of Rexinoids in NSCLC: Focus on Bexarotene (The
Explains the rationale for using rexinoids to treat cancer. Reviews past
and current studies of bexarotene (Targretin) for the treatment of NSCLC.
Concludes that Targretin shows promise for the treatment of NSCLC, citing
the survival benefit demonstrated in early studies as well as the generally
acceptable level of toxicity - specific known side effects are discussed.
Notes that results from the ongoing Phase III trials will elucidate the
role of Targretin in the treatment of NSCLC. [1/05]
I & II Pivotal Studies of Targretin IN NSCLC (Ligand
Manufacturer's press release provides update and answers to frequently
asked questions on the status of SPIRIT I & SPIRIT II, two Phase III
studies of Targretin (bexarotene) capsules in front-line combination therapy
to treat advanced NSCLC. [1/05]
(bexarotene) - Recent MEDLINE Abstracts