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Temozolomide (Temodar) : Schering-Plough : Alkylating agent

Temozolomide & Treatment of Brain Metastases
Temozolomide & Treatment of NSCLC
Temozolomide - Side Effects
Temozolomide Clinical Trials

Temozolomide & Treatment of Brain Metastases

Use of Temozolomide with Other Chemotherapy in Patients with Recurrent Brain Metastases from Lung Cancer (The Oncologist)
by Ebert, BL et al.
v.8, no.1 The Oncologist (February 2003): 69-75
Discusses the use of temozolomide with other chemotherapeutic agents as a promising strategy for treating lung cancer patients with recurrent brain metastases. [1/03]

Temozolomide Improves Outcome of Radiation Therapy in Lung Cancer with Brain Metastases (Medscape)
News release announcing the results of a study presented at the 10th World Conference on Lung Cancer in Vancouver, British Columbia, August 2003, that found the combination of temozolomide with whole-brain radiotherapy was better than whole-brain radiotherapy alone for the treatment of lung cancer with brain metastases. Registration required for free access to Medscape. [8/03]

Temozolomide in Patients with Advanced NSCLC with and without Brain Metastases: a Phase II Study of the EORTC Lung Cancer Group (PubMed)
Abstract of a study reported in the June 2003 issue of the European Journal of Cancer that evaluated the activity of single-agent temozolomide in two groups of chemotherapy-naive NSCLC patients with (12 patients) and without (13 patients) brain metastases. Reports that no objective response was observed in either group and the study was closed after the first step of accrual with the conclusion of a lack of therapeutic activity of single-agent temozolomide in patients with stage IV NSCLC. [6/03]

Temozolomide Improves Response of Brain Metastases to Radiation Therapy (Doctor's Guide)
Summarizes the results of a Phase III study presented at the 2002 annual meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) that found that adding temozolomide to whole brain radiation therapy significantly increases the response rate of patients with brain metastases. Of the 134 patients in the study, 82% had lung cancer as their primary site. [10/02]

Multicenter Phase II Study of Temozolomide Therapy for Brain Metastasis in Patients with Malignant Melanoma, Breast Cancer and NSCLC (ASCO 2003 Abstract)

Phase II Study of Temozolomide and Cisplatin in NSCLC with Brain Metastasis (ASCO 2003 Abstract)

Temozolomide & Treatment of Brain Metastases - Recent MEDLINE Abstracts



Temozolomide & Treatment of NSCLC

Evaluation of the Efficacy of Prolonged Administration of Temozolomide as a Salvage Therapy for Advanced NSCLC (ASCO 2003 Abstract)

Temozolomide in Patients with Advanced NSCLC with and without Brain Metastases: a Phase II Study of the EORTC Lung Cancer Group (PubMed)
Abstract of a study reported in the June 2003 issue of the European Journal of Cancer that evaluated the activity of single-agent temozolomide in two groups of chemotherapy-naive NSCLC patients with (12 patients) and without (13 patients) brain metastases. Reports that no objective response was observed in either group and the study was closed after the first step of accrual with the conclusion of a lack of therapeutic activity of single-agent temozolomide in patients with stage IV NSCLC. [6/03]

Temozolomide & Treatment of NSCLC - Recent MEDLINE Abstracts



Temozolomide - Side Effects

Temozolomide (CancerBACUP)
Factsheet describes Temozolomide, how it is given and some of its possible side effects. [11/02]

Temodar (temozolomide) (Schering)
Manufacturer's patient guide answers frequently-asked questions about Temodar (temozolomide).



Temozolomide Clinical Trials

Temozolomide and Brain Metastases - Clinical Trials (ClinicalTrials.gov)




 

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Last modified: 18-Feb-2009
Karen Parles, MLS Editor