General Information
Bone
Complications in Lung Cancer (HealingWell.com)
Describes bone metastasis, discusses treatment options and suggests
questions to ask your doctor. [6/02]
Bone
Metastasis Facts (Bone Metastasis Clinic, Comprehensive
Cancer Center University of Michigan)
Comprehensive information on bone metastasis, including symptoms,
diagnosis and treatment. Includes frequently asked questions about bone
metastasis.
Bone
Metastasis (bonetumor.org)
Offers a basic introduction to bone metastasis, including a section on
bone metastasis
from lung cancer. [1996]
Imaging of Bone Metastasis
Evaluation
of Bone Metastases in Lung Cancer (H.Lee Moffitt Cancer
Center)
by Poonam Malhotra, MD and Claudia G. Berman, MD
v.9, n.3 Cancer Control Journal (May/June 2002): 254-55
Case study illustrating how FDG-PET scans offer advantages over bone scans
for detecting bone metastases from lung cancer. Suggests that FDG-PET
can be useful in determining the presence of active metastatic disease
following treatment and is useful in monitoring response to therapy. (Be
sure to click on the "Discussion" button at the bottom of the page.) [2002]
MR
Imaging of the Spine is Superior to Bone Scintigraphy in Diagnosis of
Spine Metastases in Patients with NSCLC (ASCO)
Abstract of a retrospective study presented at the ASCO 2000 annual
meeting that compared bone scintigraphy (BS) with magnetic resonance imaging
(MRI) for patients with NSCLC and back pain. Study concluded that MRI
of the spine should be the first test to evaluate any patient with NSCLC
and back pain. [5/00]
Specific Therapies
Bisphosphonates
Zometa
(Lung Cancer Online)
Provides links to information on Zometa (zoledronic acid), a bisphosphonate
used to treat bone metastases from lung cancer.
Radiation Therapy
Single-
vs. Multiple-fraction Radiotherapy in Patients with Painful Bone Metastases:
Cost-Utility Analysis Based on a Randomized Trial (PubMed)
Study published in the 2/5/03 issue of the Journal of the National
Cancer Institute found that single-fraction radiotherapy provides equal
palliation and quality-of-life when compared to multiple-fraction radiotherapy
with no differences found in life expectancy. [2/03]
Radiofrequency Ablation
Radiofrequency
Ablation Effective for Pain Associated with Osteolytic Metastatic Lesions
(Medscape)
Reports on a multicenter study presented at the 2002 Radiological
Society of North America (RSNA) annual meeting that demonstrated dramatic
reductions in pain and improved quality of life in patients receiving
radiofrequency ablation (RFA) for treatment of osteolytic metastatic lesions.
Registration required for free access to Medscape. [12/02]
Radiopharmaceuticals
Quadramet:
Patient Information (Cytogen)
Manufacturer's information on Quadramet, a radiopharmaceutical designed
to relieve pain from bone metastases.
Surgical Strategies
Surgery
Provides Relief in Treating Spinal Cord Compression (People
Living With Cancer)
Reports on a study presented at the 2003 ASCO annual meeting that
found surgery followed by radiation was more effective than radiation
alone in relieving spinal cord compression. Spinal cord compression is
a painful and debilitating condition that may occur when cancer spreads
to the vertebrae and causes pressure on the spinal cord. [5/03]
Pain
from Bone Metastasis: Surgical Strategies (MD Anderson
Cancer Center)
Discusses surgical options to relieve pain from bone metastasis.
[4/01]
Vertebroplasty:
Is It Right for You? (MD Anderson Cancer Center)
Discusses the pros and cons of vertebroplasty, a technique used to
treat vertebral compression fractures, including those caused by metastatic
cancer. [12/01]
International
Conference on Bone Metastases (ICBM): Cement Filler Prevents
Bone Metastases (Doctor's Guide)
Study results reported at ICBM (June 2000) found that advanced cancer
patients with bony vertebral metastases may have prolonged pain relief
and delayed metastatic-tumor growth when the bony lesions are filled hot
plastic cement in a procedure known as vertebroplasty or cementoplasty.
The procedure can be done in conjunction with chemotherapy or radiotherapy.
[6/00]
Vertebroplasty
(Massachusetts General Hospital)
Answers frequently-asked questions about vertebroplasty: what is
vertebroplasty? what are the results of vertebroplasty? how is vertebroplasty
performed? what are the risks of vertebroplasty? who is eligible for vertebroplasty?
Includes information on pre-procedure evaluation and post-procedure care
that applies specifically to services at Mass General Hospital, however,
the general information is useful in any case. [undated]
|
