Overview of Clinical
Research
First-line
Chemotherapy Options for Patients with Advanced NSCLC (Medscape)
by Konstantin Dragnev, MD and James Rigas, MD
This article examines the first-line chemotherapy options for patients
with advanced NSCLC and reviews the major trials supporting the use of
platinum-based regimens. Aimed at physicians. Registration required for
free access to Medscape. [2/05]
Chemotherapy
& NSCLC Review Articles - Recent MEDLINE Abstracts (PubMed)
Taxane-Platinum
Combinations in Advanced NSCLC: A Review (The Oncologist)
by James R. Rigas, MD
v.9 (suppl 2) The Oncologist (June 2004): 16-23
Reviews the use of taxane chemotherapy in the treatment of NSCLC.
Identifies key findings from the four large randomized trials assessing
platinum-taxane combinations in advanced NSCLC, including efficacy, side
effect and quality of life results. Aimed at physicians. [6/04]
Is
There a Preferred Combination Chemotherapy Regimen for Metastatic NSCLC?
(The Oncologist)
by David S. Ettinger, MD
v.7, no.3 The Oncologist (June 2002): 226-233
Discusses the new chemotherapy agents (paclitaxel, docetaxel,
gemcitabine, vinorelbine, irinotecan, and topotecan) used for treatment
of advanced NSCLC. Notes that these agents have been combined with cisplatin,
carboplatin and nonplatinum drugs to produce median survival times of
8-10 months and 1 and 2 year survival rates of 35-40% and 10-15% respectively.
Based on this review, there is not a preferred combination chemotherapy
to treat advanced NSCLC patients; however, there are a number of different
regimens from which to choose. Aimed at physicians. [6/02]
Chemotherapy in Advanced
NSCLC (Medscape)
Summary, by Tracey L. Evans, MD, of results of chemotherapy trials
for NSCLC presented at ASCO 2001. Aimed at physicians. Registration required
for free access to Medscape. [5/01]
Common NSCLC Drugs &
Regimens
Camptosar (irinotecan;
CPT-11) (Lung Cancer Online)
Camptothecin
(Lung Cancer Online)
Carboplatin
(Paraplatin) (Lung Cancer Online)
Cisplatin (Platinol)
(Lung Cancer Online)
Epirubicin
(Lung Cancer Online)
Gemzar (gemcitabine)
(Lung Cancer Online)
Navelbine (vinorelbine)
( Lung Cancer Online)
Oxaliplatin
(Lung Cancer Online)
Taxol (paclitaxel)
(Lung Cancer Online)
Taxotere (docetaxel)
(Lung Cancer Online)
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