Prophylactic Cranial Irradiation
Prophylactic
Cranial Irradiation in Small-Cell Lung Cancer (The Oncologist)
5, no.4 The Oncologist (August 2000): 293-298
Excellent comprehensive review of the literature on prophylactic
cranial irradiation in SCLC patients. See also the commentary by Andrew
T. Turrisi: "PCI
in SCLC: Is It Still Controversial or Is It a No-Brainer?" in the
same issue of The Oncologist. [8/00]
Prophylactic
Cranial Irradiation (PCI) in SCLC (Cancer Care Ontario)
Aimed at physicians, this practice guideline addresses the question
of the role of PCI in SCLC patients who have achieved complete response/remission.
Discusses dose and fractionation schemes, and the effect of PCI on quality
of life (scroll down to SCLC section). [11/03]
Cranial
Irradiation for Preventing Brain Metastases of SCLC in Patients in Complete
Remission (Cochrane Collaboration)
from Cochrane Review Abstracts
Examines available evidence from randomized trials to test whether prophylactic
cranial irradiation (PCI) prolongs survival in SCLC patients in complete
remission. Concludes that PCI significantly improves overall and disease-free
survival for patients with SCLC in complete remission. Notes that further
clinical trials are needed to confirm the potential greater benefit on
brain metastasis rate suggested when PCI is given earlier or at higher
doses. [2006]
PCI
& SCLC - Recent MEDLINE Abstracts (PubMed)
PCI
& SCLC - Clinical Trials (ClinicalTrials.gov)
Palliative Brachytherapy
High-Dose-Rate
Brachytherapy (HDR-BT) Makes Palliative Radiation Effective, Convenient
for Lung Cancer Patients (Doctor's Guide)
Discusses trial results reported at the 42nd Annual Meeting of the
American Society for Therapeutic Radiology (ASTRO) that found high-dose-rate
brachytherapy (HDR-BT) is an effective palliative therapy for central
lung tumors, and that afterloading of the bronchus with two applications
appears to be more effective and convenient for patients that is the standard
four application dose. [10/00]
Radiation Sensitizers
Radiation
Sensitizers - Recent MEDLINE Abstracts
|
